One of the most crucial problems in today’s world is food insecurity, with nearly 842 million people in the world are estimated to be suffering from not regularly getting enough and healthy food for their life. This issue is likely to be exacerbated by the rapid development of biofuel industry across the globe. Hence, this study investigates the implications of biofuels on food security in 51 developing countries from 2011 to 2016. Applying generalized method of moments (GMM), our results provide supportive evidence that biofuels worsen food security in developing countries. Although our undesirable result is in line with other few past studies, we believe that this result could be the short-term phenomenon and in the long-run, more win-win guidelines for the production of biofuels and food must be provided by the government.